Trimi semaglutide review
Lowest flat price with named pharmacies. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $99 a month.
Updated 2026-09-18
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Semaglutide climbs through five doses over about five months. At Trimi, all five cost the same $99 a month on the annual plan.
That matters more for semaglutide than people expect. It is usually the drug chosen by those who want a gentler ramp, and a flat price means you can take that ramp as slowly as your stomach needs.
How the dose ladder is handled
0.25 through 2.4 mg with clinician review at each step and no price change at any of them. Requests to hold at a dose are handled through the portal rather than requiring an appointment.
| Semaglutide doses | Step up roughly every |
|---|---|
| 0.25 mg → 0.5 mg → 1 mg → 1.7 mg → 2.4 mg | 4 weeks |
| Price changes as you climb? | Check before you start |
The full schedule, and what to do if a rung goes badly, is in the dose ladder explained.
Support when it gets hard
Named 50-state clinician network, 24/7 portal, free overnight shipping, and publicly named 503A compounding pharmacies with a certificate of analysis on request.
Flat-rate compounded GLP-1 programme on annual plans, with medical oversight through the Arora Health clinician network and publicly named 503A compounding pharmacies.
What it costs
About $1,188 a year on the annual plan — tied for the cheapest honest semaglutide rate we track.
| Trimi · semaglutide | |
|---|---|
| Advertised from | $99/mo |
| Membership on top | None |
| What you actually pay | $99/mo |
| Over a year | $1,188 |
Annual-plan price, flat across the dose range, no membership behind it.
What we verified
- Compounded tirzepatide advertised at $125/month on the annual plan.
- Compounded semaglutide advertised at $99/month on the annual plan.
- Price is the same at every prescribed dose.
- One flat charge covers medication, clinician visits, check-ins and free overnight shipping; no separate membership.
- Names its compounding pharmacies publicly: VialsRx (Texas Board of Pharmacy #35264) and GreenwichRx, with a certificate of analysis available on request.
- Medical oversight via Arora Health, a 50-state network led by Dr. Sean Arora, MD.
- Advertises a six-month money-back promise subject to terms.
Checked 2026-09-18. Prices here move often, so treat anything older than a month as a starting point.
Strengths
- The cheapest verified flat rate for compounded tirzepatide in this comparison.
- Names its pharmacies with a licence number and offers a certificate of analysis — almost nobody else in this market does.
- Price does not move as your dose is adjusted.
- No membership fee stacked on the medication price.
Drawbacks
- The headline rates require an annual commitment.
- Compounded medication only, with no route to branded Zepbound or Wegovy.
- Newer and smaller than the large platforms, with a shorter public track record.
Worth knowing. Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months.
How it scored
Trimi scores 4.6 out of 5, placing it 2 of 17 for semaglutide. The weights are published on how we rate and fixed before we assess anyone.
| What we weigh | Weight | Score |
|---|---|---|
| True monthly cost | 30% | 5 / 5 |
| Price honesty | 20% | 4.8 / 5 |
| Clinical support | 20% | 4 / 5 |
| Pharmacy sourcing | 15% | 4.8 / 5 |
| Cancelling | 15% | 4.2 / 5 |
Our verdict
Cheapest, flat across the ladder, and unusually open about sourcing. If you are nervous about starting, this combination is hard to beat.
Compared with the rest
| Programme | Per month | Dose-price | Our score |
|---|---|---|---|
| Coreage Rx Best overall on true monthly cost | $149 | Flat | 4.5 |
| Trimi Lowest flat price with named pharmacies | $99 | Varies | 4.6 |
| PlexusDx Pharmacy transparency and genetic testing | $189 | Varies | 4.4 |
| Ozari Health Lowest advertised semaglutide price | $86 | Varies | 4.4 |
| Ivím Health Unlimited clinician access | $199 | Varies | 4 |
| Mochi Health Insurance concierge support | $178 incl. $79 fee | Varies | 3.6 |
| Coby Health Multi-month value with supplies included | $229 | Varies | 3.6 |
| Hims & Hers Widest range of formats | $188 incl. $39 fee | Varies | 3.5 |
Read next
- Coreage Rx semaglutide review
Best overall on true monthly cost. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $149 a month.
- PlexusDx semaglutide review
Pharmacy transparency and genetic testing. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $189 a month.
- Ozari Health semaglutide review
Lowest advertised semaglutide price. How they handle your dose ladder, what support looks like when side effects hit, and what you actually pay — $86 a month.
- Best programmes if this is your first time
Ranked on how they price the dose ladder and how reachable support is — the two things that decide whether a beginner stays on treatment.
- Your first injection
What actually happens, step by step. It is a very small needle and it goes into fat, not muscle.
- The dose ladder
Why you start low, how fast you climb, and why the price of each rung matters more than people expect.